Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century,Chemical Reviews

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Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century
Chemical Reviews ( IF 51.4 ) Pub Date : 2022-06-08 , DOI: 10.1021/acs.chemrev.2c00029
Yashapal Singh ₁ , Scott A Geringer ₁ , Alexei V Demchenko _{1,

2}

Affiliation

Advances in synthetic carbohydrate chemistry have dramatically improved access to common glycans. However, many novel methods still fail to adequately address challenges associated with chemical glycosylation and glycan synthesis. Since a challenge of glycosylation has remained, scientists have been frequently returning to the traditional glycosyl donors. This review is dedicated to glycosyl halides that have played crucial roles in shaping the field of glycosciences and continue to pave the way toward our understanding of chemical glycosylation.

中文翻译：

异头卤化物的合成和糖苷化：从早期研究到 21 世纪现代方法的演变

合成碳水化合物化学的进步极大地改善了常见聚糖的获取。然而，许多新方法仍然无法充分解决与化学糖基化和聚糖合成相关的挑战。由于糖基化的挑战仍然存在，科学家们经常回归传统的糖基供体。这篇综述致力于糖基卤化物，它们在糖科学领域的发展中发挥了至关重要的作用，并继续为我们理解化学糖基化铺平道路。

更新日期：2022-06-08

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