Background:In recent decades, the prevalence of asthma has substantially increased worldwide. Advancesin phytochemistry and phytopharmacology have clarified the active ingredients and biological activitiesof medicinal plant products for treating asthma, and the role of herbal therapies in asthma treatment has becomeincreasingly evident. However, most plant extracts have low solubility and poor stability of bioactive components,resulting in low bioavailability and loss of efficacy. Owing to these shortcomings, the clinical use ofmany herbal extracts is limited.Objective:To summarise and analyse the characteristics of herbal nanoformulations and their application inasthma treatment. The objective of this review article is to address the emerging trends of herbal nanoformulationsfor an effective treatment of asthma.Methods:Various research and review articles from reputed international journals were referred to andcompiled.Results:The nano-sized herbal formulations improve the solubility and bioavailability of herbal medicines andcontribute to the sustained release of drugs, thus, increasing the therapeutic applications of herbal extracts. Thereview present different types of herbal nanoformulations, including micelles, nanoparticles, solid lipid nanoparticles,lipid-based liquid crystalline nanoparticles and nanoemulsions, which are potential nanodrugs for asthmatreatment.Conclusions:Herbal nanoformulations have shown great prospects for the treatment of asthma in recent years.More safety and toxicity data are still needed to promote their development and application.

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用于哮喘治疗的草药纳米制剂

背景：近几十年来，哮喘的患病率在全球范围内大幅增加。植物化学和植物药理学的进展已经阐明了治疗哮喘的药用植物产品的活性成分和生物活性，草药疗法在哮喘治疗中的作用日益明显。然而，大多数植物提取物溶解度低，生物活性成分稳定性差，导致生物利用度低，失去药效。由于这些不足，许多中草药提取物的临床应用受到限制。目的：总结和分析中草药纳米制剂的特点及其在哮喘治疗中的应用。这篇综述文章的目的是探讨用于有效治疗哮喘的草药纳米制剂的新兴趋势。方法：参考并整理了国际知名期刊的各种研究和评论文章。结果：纳米级草药制剂提高了草药的溶解度和生物利用度，有助于药物的缓释，从而增加了草药提取物的治疗应用。综述了目前不同类型的中草药纳米制剂，包括胶束、纳米粒、固体脂质纳米粒、脂质基液晶纳米粒和纳米乳，它们是潜在的哮喘治疗纳米药物。结论：中草药纳米制剂近年来在哮喘治疗中显示出广阔的前景。仍需要更多的安全性和毒性数据来促进其开发和应用。纳米级的草药制剂提高了草药的溶解度和生物利用度，有助于药物的缓释，从而增加了草药提取物的治疗应用。综述了目前不同类型的中草药纳米制剂，包括胶束、纳米粒、固体脂质纳米粒、脂质基液晶纳米粒和纳米乳，它们是潜在的哮喘治疗纳米药物。结论：中草药纳米制剂近年来在哮喘治疗中显示出广阔的前景。仍需要更多的安全性和毒性数据来促进其开发和应用。纳米级的草药制剂提高了草药的溶解度和生物利用度，有助于药物的缓释，从而增加了草药提取物的治疗应用。综述了目前不同类型的中草药纳米制剂，包括胶束、纳米粒、固体脂质纳米粒、脂质基液晶纳米粒和纳米乳，它们是潜在的哮喘治疗纳米药物。结论：中草药纳米制剂近年来在哮喘治疗中显示出广阔的前景。仍需要更多的安全性和毒性数据来促进其开发和应用。