Smartphone-based photochemical sensor for multiplex determination of glucose, uric acid, and total cholesterol in fingertip blood,Analyst

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Smartphone-based photochemical sensor for multiplex determination of glucose, uric acid, and total cholesterol in fingertip blood
Analyst ( IF 3.6 ) Pub Date : 2022-06-07 , DOI: 10.1039/d2an00764a
Wenfang Duan ₁ , Jie Cheng ₂ , Jinhong Guo _{1,

2}

Affiliation

A smartphone-based photochemical biosensor capable of realizing multiplex detection of glucose, uric acid (UA), and total cholesterol (TC) is reported here for the first time. The system was composed of a photochemical dongle, a cloud-enabled smartphone, and disposable test strips. The dongle was controlled using a microcontroller unit and was designed to convert the reflected light's intensities into optoelectronic signals for analytes quantification. Only 30 μL of the fingertip blood is needed to complete accurate and reliable measurements within 2 minutes. A cloud-enabled smartphone is connected to the dongle via Bluetooth to serve as a data receiver, and users can obtain the test results for proactive health management or remote diagnosis, while powering the dongle. We believe the proposed biosensor will contribute a lot to the point-of-care-testing and has promising prospects in contributing to the development of the Internet of Medical Things.

中文翻译：

基于智能手机的光化学传感器用于多重测定指尖血液中的葡萄糖、尿酸和总胆固醇

本文首次报道了一种基于智能手机的光化学生物传感器，能够实现葡萄糖、尿酸（UA）和总胆固醇（TC）的多重检测。该系统由光化学加密狗、支持云的智能手机和一次性测试条组成。加密狗使用微控制器单元进行控制，旨在将反射光的强度转换为用于分析物量化的光电信号。仅需 30 μL 指尖血液即可在 2 分钟内完成准确可靠的测量。支持云的智能手机通过以下方式连接到加密狗蓝牙作为数据接收器，用户可以在为加密狗供电的同时获取测试结果进行主动健康管理或远程诊断。我们相信，所提出的生物传感器将为即时检测做出很大贡献，并在促进医疗物联网的发展方面具有广阔的前景。

更新日期：2022-06-07

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