Abstract

Background: Neuroglial heterotopia, characterized by mature ­neuroglial tissue outside the central nervous system, has not been previously associated with cranioschisis. Case Report: A 4-year-old female patient, with left congenital anophthalmia, had a nasofrontal neuroglial heterotopia protruding through an ossification defect. Discussion: Nasofrontal cranioschisis may be associated with neuroglial heterotopias. The combination of anophthalmia and neuroglial heterotopia, previously described only once in the literature, may be part of a broader malformation spectrum that has not been properly characterized to date.

中文翻译：

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与硬膜外神经胶质细胞异位相关的单侧无眼症和先天性额骨裂：对可能的新畸形谱的新见解

摘要

背景：神经胶质异位症，其特征是中枢神经系统外的成熟神经胶质组织，以前未与颅分裂相关。病例报告：一名 4 岁女性患者，患有左侧先天性无眼症，鼻额神经胶质异位通过骨化缺损突出。讨论：鼻额颅裂可能与神经胶质异位有关。无眼畸形和神经胶质异位症的组合，以前在文献中仅描述过一次，可能是迄今为止尚未正确表征的更广泛的畸形谱的一部分。