In individuals with Down syndrome, immune dysregulation is partially caused by chromosome 21 trisomy. Here, we discuss how these immune differences may result in poorer COVID-19 outcomes, including diminished responses to vaccination and possibly elevated risk for long COVID.

中文翻译：

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COVID-19 和唐氏综合症：燃料中的火花


在唐氏综合症患者中，免疫失调部分是由 21 号染色体三体引起的。在这里，我们讨论这些免疫差异如何导致 COVID-19 结果较差，包括对疫苗接种的反应减弱以及长期感染 COVID 的风险可能升高。