Bisphenol A (BPA) and polystyrene (PS) microplastics have attracted much attention because they are widely distributed in the environment, while their combined toxicity to aquatic organisms has rarely been studied. Therefore, this study explored the impact of microplastics on the toxic effects and biodegradation of BPA to the microalgae Chlorella pyrenoidosa. The results indicated that during the 16 days culture, PS (5 mg/L) increased the growth inhibition of BPA (1 mg/L and 10 mg/L) on C. pyrenoidosa compared to without PS. Similarly, PS (5 mg/L and 100 mg/L) also increased the degradation efficiency of BPA (1 mg/L and 10 mg/L) by algae. However, the changes of the chlorophyll content and the Fv/Fm value were opposite due to the hermetic and shading effect. Moreover, this study also found that five intermediates were formed during BPA degradation process because of the presence of oxidoreductase and glycosyltransferase. The results of the study provided vital information on the effect of PS on the toxicity and biodegradation of BPA to microalgal.

双酚A（BPA）和聚苯乙烯（PS）微塑料因其在环境中广泛分布而备受关注，而它们对水生生物的综合毒性却鲜有研究。因此，本研究探讨了微塑料对 BPA 对微藻Chlorella pyrenoidosa的毒性作用和生物降解的影响。结果表明，在 16 天的培养过程中，PS（5 mg/L）增加了 BPA（1 mg/L 和 10 mg/L）对C. pyrenoidosa的生长抑制作用。与没有PS相比。同样，PS（5 mg/L 和 100 mg/L）也提高了藻类对 BPA（1 mg/L 和 10 mg/L）的降解效率。然而，由于密封和遮光作用，叶绿素含量和Fv/Fm值的变化是相反的。此外，本研究还发现，由于氧化还原酶和糖基转移酶的存在，在 BPA 降解过程中形成了五种中间体。研究结果提供了关于 PS 对 BPA 对微藻的毒性和生物降解影响的重要信息。