The inevitable presence of metal ions in the slurry significantly impacts the adsorption of organic depressants. In this study, the influence of Fe³⁺ and Ca²⁺ on the depression of chalcopyrite by carboxymethyl cellulose (CMC) was investigated. CMC slightly depressed chalcopyrite flotation, and the addition of Ca²⁺ hardly impact its depression effect. However, the pre-treatment with Fe³⁺ enhanced its depression effect severely at acid conditions, while this hydrophilic strengthening effect gradually disappeared under alkaline conditions. CMC physically attached to blank chalcopyrite surface, the surface modification with FeCl₃ not only increased its adsorption capacity on chalcopyrite surface but also altered it from physical adsorption to chemical adsorption. Cu and Fe sites were not involved in CMC adsorption on blank chalcopyrite surface, and the strongly electrostatic repulsion hindered its adhesion under alkaline conditions. After surface modification with FeCl₃, electrostatic repulsion was weakened, and Fe sites participated in the bonding with CMC molecule. Thus, chalcopyrite was strongly depressed. However, the contents of Fe³⁺, Fe(OH)²⁺ and Fe(OH)₂⁺ on modified chalcopyrite were much less at strong alkaline conditions than acid conditions, which not favored CMC attachment.

浆液中不可避免地存在金属离子显着影响有机抑制剂的吸附。本研究研究了Fe ³⁺和Ca ²⁺对羧甲基纤维素（CMC）抑制黄铜矿的影响。CMC对黄铜矿浮选有轻微抑制作用，Ca ²⁺的添加对其抑制效果影响不大。^{然而，Fe 3+}预处理在酸性条件下显着增强了其抑制作用，而这种亲水强化作用在碱性条件下逐渐消失。CMC物理附着在空白黄铜矿表面，用FeCl _{3进行表面改性}不仅增加了其在黄铜矿表面的吸附能力，而且将其从物理吸附转变为化学吸附。Cu和Fe位点不参与CMC在空白黄铜矿表面的吸附，强静电排斥阻碍了其在碱性条件下的粘附。_{FeCl 3}表面改性后，静电斥力减弱，Fe位点参与与CMC分子的键合。因此，黄铜矿受到强烈抑制。但在强碱性条件下改性黄铜矿上的Fe ³⁺、Fe(OH) ²⁺和Fe(OH) ₂ ⁺含量远低于酸性条件，不利于CMC的附着。