In this issue of Cell Stem Cell, Simunovic et al. (2022) establish embryoids by combining embryonic and extraembryonic components derived from human pluripotent stem cells. The embryoids resemble human embryos cultured to post-implantation stages in vitro with regard to morphology, symmetry breaking, and the formation of primitive streak-like cell types.

中文翻译：

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人类胚胎模型破解对称破缺

在本期Cell Stem Cell中，Simunovic 等人。(2022) 通过结合源自人类多能干细胞的胚胎和胚胎外成分来建立类胚。胚状体在形态、对称性破坏和原始条纹样细胞类型的形成方面类似于体外培养到植入后阶段的人类胚胎。