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Poly(m6A) tails stabilize transcripts
Molecular Cell ( IF 14.5 ) Pub Date : 2022-06-02 , DOI: 10.1016/j.molcel.2022.05.017 Guillaume Lavergne 1 , Jean-Yves Roignant 2
中文翻译:
Poly(m6A) 尾稳定转录本
更新日期:2022-06-03
Molecular Cell ( IF 14.5 ) Pub Date : 2022-06-02 , DOI: 10.1016/j.molcel.2022.05.017 Guillaume Lavergne 1 , Jean-Yves Roignant 2
Affiliation
Viegas et al. (2022) discover that in Trypanosoma brucei the poly(A) tails of the variant surface glycoprotein (VSG) transcripts are methylated, a mechanism that stabilizes these transcripts and ensures protection against the immune response in mammals.
中文翻译:
Poly(m6A) 尾稳定转录本
维加斯等人。(2022) 发现在布氏锥虫中,变体表面糖蛋白 (VSG) 转录物的 poly(A) 尾部被甲基化,这是一种稳定这些转录物并确保保护免受哺乳动物免疫反应的机制。