To date, therapeutic approaches for cementum regeneration are limited and outcomes remain unpredictable. A significant barrier to improve therapies for cementum regeneration is that the cementocyte and its intracellular signal transduction mechanisms remain poorly understood. This study aims to elucidate the regulatory mechanism of Wnt pathway in cementogenesis.

中文翻译：

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典型的 Wnt/β-catenin 信号传导对成骨有积极影响，但对牙骨质形成有负面影响

迄今为止，牙骨质再生的治疗方法有限，而且结果仍然无法预测。改善牙骨质再生疗法的一个重要障碍是牙骨质细胞及其细胞内信号转导机制仍然知之甚少。本研究旨在阐明 Wnt 通路在牙骨质形成中的调控机制。