Duration of Antibiotic Therapy and Timing of Shunt Reimplantation in Pediatric CSF Shunt Infections: A Retrospective Multicenter Case Series.,Journal of the Pediatric Infectious Diseases Society

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Duration of Antibiotic Therapy and Timing of Shunt Reimplantation in Pediatric CSF Shunt Infections: A Retrospective Multicenter Case Series.
Journal of the Pediatric Infectious Diseases Society ( IF 2.5 ) Pub Date : 2022-08-30 , DOI: 10.1093/jpids/piac037
Joan L Robinson ₁ , Alastair McAlpine ₂ , Michelle Barton ₃ , Archana Balamohan ₄ , H Dele Davies ₅ , Gwenn Skar ₅ , Marie-Astrid Lefebvre ₆ , Ahmed Almadani ₆ , Dolores Freire ₁ , Nicole Le Saux ₇ , Jennifer Bowes ₇ , Jocelyn A Srigley ₈ , Patrick Passarelli ₉ , John Bradley ₉ , Sarah Khan ₁₀ , Rupeena Purewal ₁₁ , Isabelle Viel-Thériault ₁₂ , Michael T Hawkes ₁

Affiliation

Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Pediatrics, Health Sciences Centre, Western University, London, Ontario, Canada.
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Department of Pediatrics, McGill University, Montreal, Quebec, Canada.
Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada.
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Pediatrics, UC San Diego School of Medicine, San Diego, California, USA.
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Department of Pediatrics, CHU de Québec-Université Laval, Québec City, Quebec, Canada.

In this retrospective multicenter series of 154 children with cerebrospinal fluid shunt infections, the median (interquartile range) duration of antibiotic therapy was 18 (14-26) days. The time to shunt replacement was 14 (10-19) days. Management appeared to potentially differ according to the targeted pathogen and site.

中文翻译：

小儿脑脊液分流感染中抗生素治疗的持续时间和分流再植的时间：回顾性多中心病例系列。

在这项包含 154 名脑脊液分流感染儿童的回顾性多中心系列研究中，抗生素治疗的中位（四分位距）持续时间为 18 (14-26) 天。分流更换的时间为 14 (10-19) 天。根据目标病原体和部位的不同，管理似乎可能有所不同。

更新日期：2022-05-27

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