Itaconate is an immunomodulatory Krebs cycle-derived metabolite. Description of two isomers of itaconate, mesaconate and citraconate, which have overlapping and distinct properties when compared with itaconate in macrophages, expands the knowledge of this intriguing family of immunomodulatory metabolites.

中文翻译：

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衣康酸家族的免疫调节剂增长

衣康酸盐是一种免疫调节的克雷布斯循环衍生代谢物。对衣康酸的两种异构体中康酸和柠康酸的描述，与巨噬细胞中的衣康酸相比具有重叠和不同的特性，扩展了对这一有趣的免疫调节代谢物家族的认识。