This study shows that systemic hypoxia alters the response of the bone marrow to inflammation by reducing type I interferon signaling and suppressing the accumulation of monocyte-derived macrophages in the lung. These events, in turn, hinder the resolution of lung inflammation.

中文翻译：

---

全身性缺氧通过抑制单核细胞驱动炎症持续存在

这项研究表明，全身性缺氧通过减少 I 型干扰素信号传导和抑制肺中单核细胞衍生的巨噬细胞的积累来改变骨髓对炎症的反应。这些事件反过来又阻碍了肺部炎症的消退。