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Visible-Light-Enabled Photosensitizer- and Additive-Free Decarboxylative Coupling Cyclization of Enaminone with N-Arylglycine for 3-Aminoalkyl Chromones
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2022-05-30 , DOI: 10.1002/adsc.202200304
Zhi-Qiang Zhu 1 , Jia-Yu Hu 1 , Zong-Bo Xie 2 , Juan Tang 3 , Zhang-Gao Le 4
Affiliation  

An photosensitizer- and additive-free, visible-light-induced decarboxylative aminoalkylation/C−O coupling cyclization of enaminones with N-arylglycine for the synthesis of 3-aminoalkyl chromones has been achieved. This synthetic method features good functional-group tolerance, mild reaction conditions and no request of photocatalyst or additive, thus making this protocol more practical and sustainable.

中文翻译:

烯胺酮与 N-芳基甘氨酸的可见光光敏剂和无添加剂脱羧偶联环化用于 3-氨基烷基色酮

已经实现了一种不含光敏剂和添加剂、可见光诱导的脱羧氨基烷基化/C-O 偶联环化烯胺酮与N-芳基甘氨酸合成 3-氨基烷基色酮的方法。该合成方法具有良好的官能团耐受性、反应条件温和、无需光催化剂或添加剂等特点,使该方案更具实用性和可持续性。
更新日期:2022-05-30
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