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Twelve-week standard of care protocol longer than median time to normalization among IIc hips treated with Pavlik harness
Journal of Pediatric Orthopaedics B ( IF 0.9 ) Pub Date : 2022-07-01 , DOI: 10.1097/bpb.0000000000000946
Reba L. Salton 1 , Patrick Carry 1, 2 , Tyler Freeman 2 , Kaley Holmes 1 , Nancy H. Miller 2, 3 , Brian Kohuth 3 , Deborah Burke 3 , Matthew Belton 2 , Margaret Siobhan Murphy-Zane 2, 3 , Gaia Georgopoulos 2, 3
Affiliation  

Best treatment protocols for infants with developmental dysplasia of the hip (DDH) are poorly defined. This study estimates the time to normalization among Graf IIc hips undergoing Pavlik harness treatment. Following institutional review board approval, patients referred for DDH evaluation at a pediatric institution between 2009 and 2018 (n = 1424 hips/712 patients) were identified. We isolated all Graf IIc hips that underwent Pavlik harness treatment (n = 132 hips/n = 106 patients). Demographic and outcome measures were collected. Normalization was defined as alpha angle greater than or equal to 60° and femoral head coverage greater than or equal to 50%. Kaplan–Meier and Cox proportional hazards regression analyses modeled time to normalization and identified factors associated with earlier normalization. Median time to normalization was 7.0 weeks. At 12 weeks standard treatment, 85.8% [95% confidence interval (CI): 80.2–91.9%] had normalized. Greater femoral head coverage [hazard ratio (HR) per 1% increase: 1.03; 95% CI: 1.01–1.05; P = 0.0068] and hip stability at treatment initiation (HR unstable vs. stable: 0.64; 95% CI: 0.44–0.93; P = 0.0192) were associated with longer time to normalization. Some patients may not need 12 weeks of Pavlik bracing, particularly those with stable presentation who normalize before week 12. Shorter treatment lengths offer benefit without sacrificing long-term outcomes. Findings reinforce growing evidence that femoral head coverage should be a more significant consideration during diagnosis and instability is a concerning finding on examination.



中文翻译:

在使用 Pavlik 安全带治疗的 IIc 髋关节中,12 周的标准护理方案比正常化的中位时间长

发育性髋关节发育不良 (DDH) 婴儿的最佳治疗方案尚不明确。这项研究估计了接受 Pavlik 线束治疗的 Graf IIc 髋关节正常化的时间。在机构审查委员会批准后,确定了 2009 年至 2018 年间在儿科机构进行 DDH 评估的患者(n = 1424 髋/712 名患者)。我们分离出所有接受 Pavlik 吊带治疗的 Graf IIc 髋部(n = 132 髋/ n= 106 名患者)。收集了人口统计和结果测量。标准化定义为α角大于或等于60°且股骨头覆盖率大于或等于50%。Kaplan-Meier 和 Cox 比例风险回归分析模拟了标准化时间,并确定了与早期标准化相关的因素。正常化的中位时间为 7.0 周。在 12 周的标准治疗中,85.8% [95% 置信区间 (CI):80.2–91.9%] 已正常化。更大的股骨头覆盖率 [风险比 (HR) 每增加 1%:1.03;95% CI:1.01–1.05;P = 0.0068] 和治疗开始时的髋关节稳定性(HR 不稳定与稳定:0.64;95% CI:0.44–0.93;P= 0.0192)与更长的标准化时间相关。一些患者可能不需要 12 周的 Pavlik 支具,特别是那些在 12 周前恢复正常的表现稳定的患者。较短的治疗时间可以在不牺牲长期结果的情况下提供益处。研究结果强化了越来越多的证据,即股骨头覆盖应该是诊断期间更重要的考虑因素,而不稳定是检查时的一个令人担忧的发现。

更新日期:2022-05-31
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