Development of well-defined multivalent systems with densely packed multiple functional groups located within a single molecular structure provides an excellent opportunity to generate catalysts of enhanced activity. A series of mono-, di- and trinuclear Pd(II) complexes based on polyketonate ligands allied with 2,2′-bipyridine has been designed, synthesized and fully characterized in both solution and solid state. The mono-, di- and tritopic β-diketonate molecules serve as scaffolds for Pd(II) active sites which, in the two latter cases, are forced into close proximity. Application of the complexes as catalysts in Suzuki-Miyaura cross-coupling as a model reaction has revealed significant differences in reaction yields and a trend in reactivity reflecting their nuclearity.

开发具有位于单个分子结构内的密集排列的多个官能团的定义明确的多价体系，为生成具有增强活性的催化剂提供了极好的机会。已经设计、合成了一系列基于与 2,2'-联吡啶结合的聚酮配体的单核、双核和三核 Pd(II) 配合物，并在溶液和固态下进行了充分表征。单分子、双分子和三分子 β-二酮分子充当 Pd(II) 活性位点的支架，在后两种情况下，这些活性位点被迫靠近。将配合物作为催化剂在 Suzuki-Miyaura 交叉偶联中作为模型反应的应用揭示了反应产率的显着差异和反映其核性的反应性趋势。