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Sex differences of oestradiol-mediated gene expression
Nature Reviews Genetics ( IF 39.1 ) Pub Date : 2022-05-26 , DOI: 10.1038/s41576-022-00507-3
Katharine H Wrighton 1
Affiliation  

Gegenhuber et al. now show that, in mice, a neonatal surge in oestradiol activates oestrogen receptor-α to drive a sustained male-typical gene expression programme that determines brain sexual differentiation.

中文翻译:

雌二醇介导的基因表达的性别差异

Gegenhuber 等人。现在表明,在小鼠中,雌二醇的新生儿激增会激活雌激素受体-α,从而驱动一个持续的男性典型基因表达程序,该程序决定了大脑的性别分化。
更新日期:2022-05-27
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