Merging the Non-Natural Catalytic Activity of Lipase and Electrosynthesis: Asymmetric Oxidative Cross-Coupling of Secondary Amines with Ketones,Angewandte Chemie International Edition

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Merging the Non-Natural Catalytic Activity of Lipase and Electrosynthesis: Asymmetric Oxidative Cross-Coupling of Secondary Amines with Ketones
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2022-05-27 , DOI: 10.1002/anie.202203666
Chao-Jiu Long ₁ , Huan Cao ₁ , Ben-Kun Zhao ₁ , Yu-Fang Tan ₁ , Yan-Hong He ₁ , Chu-Sheng Huang ₂ , Zhi Guan ₁

Affiliation

An asymmetric oxidative cross-coupling strategy that combines the non-natural catalytic activity of lipase with organic electrosynthesis was developed. This unprecedented protocol demonstrates that hydrolase catalysis is compatible with electrosynthesis.

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