Large-scale clinical studies on the post-infectious impacts of SARS-CoV-2 have suggested that patients who have recovered from acute infection have increased risk for cardiometabolic syndrome-associated morbidities such as diabetes, chronic kidney disease and heart failure. Initial studies have taken the first steps towards unravelling the molecular processes that may be driving these findings, including the role of immune and inflammatory factors, but a comprehensive aetiology remains unclear. Given that cardiometabolic syndrome progression in patients with Long COVID may pose a significant global health and economic burden post pandemic, there is an emergent need to identify therapeutic targets and treatment options. Among the multi-organ complications of Long COVID, those associated with cardiometabolic syndrome were some of the most prevalent in recent studies of population-scale data. Given the potential health and economic burdens, there is an urgent need to better define the inflammatory processes involved.

中文翻译：

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心脏代谢综合征——Long COVID 的一个新兴特征？

关于 SARS-CoV-2 感染后影响的大规模临床研究表明，从急性感染中康复的患者患心脏代谢综合征相关疾病的风险增加，例如糖尿病、慢性肾病和心力衰竭。初步研究已迈出第一步，以揭示可能推动这些发现的分子过程，包括免疫和炎症因子的作用，但全面的病因仍不清楚。鉴于 Long COVID 患者的心脏代谢综合征进展可能会在大流行后对全球健康和经济造成重大负担，因此迫切需要确定治疗目标和治疗方案。在 Long COVID 的多器官并发症中，在最近的人口规模数据研究中，与心脏代谢综合征相关的那些是最普遍的。鉴于潜在的健康和经济负担，迫切需要更好地定义所涉及的炎症过程。