Activation of resting regulatory T cells (Tregs) upon antigen encounter is essential for proper Treg function. However, the metabolic pathways that mediate this transition are unknown. Liu et al. have identified the non-oxidative pentose phosphate pathway as a central regulator of Treg activation and function.

中文翻译：

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TKT 缺乏使 Tregs 休息

在遇到抗原时激活静息调节性 T 细胞 (Tregs) 对于正常的 Treg 功能至关重要。然而，介导这种转变的代谢途径是未知的。刘等人。已经确定非氧化戊糖磷酸途径作为Treg活化和功能的中央调节剂。