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Incidence of Thirty-day MACE among patients presenting to emergency department with low-risk chest pain in a tertiary care hospital: A prospective study
medRxiv - Emergency Medicine Pub Date : 2022-05-21 , DOI: 10.1101/2022.05.17.22275224
Sanwar Khokhar , Abhishek Jaiswal , Raman Abhi , Mohammed Hasnain Reza

Background: Current guidelines for low-risk chest pain patients recommend obtaining serial ECGs and serial measurements of cardiac troponin between 6 and 12 hours. As a result, the majority of patients require prolonged assessment before safe discharge. There is a need to identify these patients promptly to help in reducing the time to provide the treatment as well as reduce the burden over the ED. Present study was done with the objective of estimating the incidence of thirty-day Major Averse Cardiac Event (MACE) in patients presenting to emergency department with low-risk chest pain, and to compare the Thrombolysis In Myocardial Infarction (TIMI), HEART and Emergency Department Assessment of Chest Pain Score (EDACS) Score in patients with low-risk chest pain. Methods: Present study was descriptive follow up study done at a tertiary care hospital (Fortis Memorial Research Institute, in Gurugram, Haryana, India. Study was conducted from Jan 2018 to Jan 2019. All the patient reporting with low-risk chest pain during study period were recruited in the study. Semi-structured interview schedule was used for the data collection. Outcome variable was MACE (Major adverse cardiac event) event in 30 days. Results: Total 156 participants were included in the study. Mean age of participants was 44.1 years. Out of 156 participants, 10 (6.4%) reported MACE in 30 days of presentation. We found that HEART and EDACS score had incidence of MACE less than 2% in their low-risk groups and TIMI score had incidence of MACE >2% in its low-risk group. Conclusion: EDACS and HEART score can be used in the Emergency department to identify the low-risk chest pain patients. This could help in early identification and save time and other resources.

中文翻译:

三级医院急诊科就诊的低危胸痛患者 30 天 MACE 的发生率:一项前瞻性研究

背景:目前针对低危胸痛患者的指南建议在 6 至 12 小时内获得连续心电图和连续测量心肌肌钙蛋白。因此,大多数患者在安全出院前需要进行长时间的评估。有必要及时识别这些患者,以帮助减少提供治疗的时间并减轻 ED 的负担。本研究旨在评估因低危胸痛到急诊科就诊的患者 30 天主要心脏不良事件 (MACE) 的发生率,并比较心肌梗塞 (TIMI)、心脏和急诊的溶栓低危胸痛患者的胸痛评分科室评估 (EDACS) 评分。方法:EDACS 和 HEART 评分可用于急诊科识别低危胸痛患者。这有助于早期识别并节省时间和其他资源。
更新日期:2022-05-24
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