AIMS This study assessed contributions of exposure to neighborhood stressors (violent victimization, witnessing crime, greater alcohol and drug availability) to variation in alcohol use disorder (AUD) symptoms among drinkers in three cities in Texas, USA. METHODS We used data from interviews conducted from 2011 to 2013 with Mexican-origin adults (ages 16-65) in the US-Mexico Study of Alcohol and Related Conditions who were past-year drinkers (N = 1960; 55% male) living in two cities in the Texas-Mexico border region (Laredo, n = 751 and Brownsville/McAllen, n = 814) and one interior comparison site (San Antonio, n = 771). Analyses (conducted in 2018 and 2019) examined overall and gender-stratified multilevel mediated effects of each border site (versus San Antonio) on AUD symptoms through the neighborhood-level factors, adjusting for individual- and neighborhood-level covariates. RESULTS Overall, drinkers in Laredo reported more AUD symptoms than drinkers in the other cities, and their neighborhoods had more witnessing of crime and greater perceived drug availability, as well as higher levels of disadvantage and a lower proportion non-Hispanic White residents, than neighborhoods in San Antonio. Witnessing neighborhood crime was associated with increased AUD symptoms, while neighborhood disadvantage and proportion non-Hispanic White residents each were negatively associated with AUD symptoms. Perceived neighborhood insecurity, crime victimization, perceived neighborhood drug availability and neighborhood alcohol availability (off- and on-premise) were not significantly associated with AUD symptoms. Stratified models suggested possible gender differences in indirect effects through witnessing neighborhood crime. CONCLUSION Reducing witnessing of neighborhood crime may help reduce AUD symptoms among adults living in the US border region.

中文翻译：

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居住在美墨边境地区的墨西哥裔美国人的邻里环境和饮酒障碍。

目的 本研究评估了暴露于邻里压力源（暴力受害、目睹犯罪、更多的酒精和药物供应）对美国德克萨斯州三个城市饮酒者酒精使用障碍 (AUD) 症状变化的影响。方德克萨斯-墨西哥边境地区的两个城市（拉雷多，n = 751 和布朗斯维尔/麦卡伦，n = 814）和一个内部比较站点（圣安东尼奥，n = 771）。分析（在 2018 年和 2019 年进行）通过社区层面的因素检查了每个边境站点（相对于圣安东尼奥）对 AUD 症状的整体和性别分层的多层次中介效应，调整个人和社区级别的协变量。结果 总体而言，拉雷多的饮酒者比其他城市的饮酒者报告了更多的 AUD 症状，他们的社区比其他社区有更多的犯罪见证和更多的毒品供应，以及更高的劣势和更低的非西班牙裔白人居民比例在圣安东尼奥。目击邻里犯罪与 AUD 症状增加有关，而邻里劣势和非西班牙裔白人居民比例均与 AUD 症状呈负相关。感知到的邻里不安全感、犯罪受害、感知到的邻里毒品供应和邻里酒精供应（场外和场内）与 AUD 症状没有显着相关性。分层模型表明，通过目睹邻里犯罪，间接影响可能存在性别差异。结论 减少对邻里犯罪的目击可能有助于减少居住在美国边境地区的成年人的 AUD 症状。