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The human pituitary master gland stripped to single-cell resolution
Nature Reviews Endocrinology ( IF 31.0 ) Pub Date : 2022-05-20 , DOI: 10.1038/s41574-022-00696-1 Emma Laporte 1 , Hugo Vankelecom 1
Nature Reviews Endocrinology ( IF 31.0 ) Pub Date : 2022-05-20 , DOI: 10.1038/s41574-022-00696-1 Emma Laporte 1 , Hugo Vankelecom 1
Affiliation
Stem cells in the pituitary master gland remain mystifying; moreover, they have hardly been explored in humans. A new study applied transcriptome and chromatin accessibility profiling at single-cell resolution to human postmortem pituitary glands from individuals of different ages, thereby providing insights into the heterogeneity and regulatory mechanisms of the projected human pituitary stem cell population.
中文翻译:
剥离至单细胞分辨率的人类垂体主腺
垂体主腺中的干细胞仍然神秘莫测;此外,它们几乎没有在人类身上进行过探索。一项新研究将单细胞分辨率的转录组和染色质可及性分析应用于不同年龄个体的死后垂体,从而深入了解预计的人类垂体干细胞群的异质性和调节机制。
更新日期:2022-05-22
中文翻译:
剥离至单细胞分辨率的人类垂体主腺
垂体主腺中的干细胞仍然神秘莫测;此外,它们几乎没有在人类身上进行过探索。一项新研究将单细胞分辨率的转录组和染色质可及性分析应用于不同年龄个体的死后垂体,从而深入了解预计的人类垂体干细胞群的异质性和调节机制。