The Role of Zinc in GM-CSF-Induced Signaling in Human Polymorphonuclear Leukocytes,Molecular Nutrition & Food Research

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The Role of Zinc in GM-CSF-Induced Signaling in Human Polymorphonuclear Leukocytes
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-05-20 , DOI: 10.1002/mnfr.202101106
Marijke van der Laan ₁ , Anna Büttgenbach ₁ , Jana Wolf ₁ , Lothar Rink ₁ , Inga Wessels ₁

Affiliation

Zinc is suggested to be necessary for functional signaling induced by certain growth factors. The granulocyte-macrophage colony-stimulating factor (GM-CSF) is a key factor for differentiation and activation of myeloid cells. This report analyses the impact of different zinc concentrations on GM-CSF-induced signaling in mature polymorphonuclear leukocytes (PMN).

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