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Why you always in a mood? Pumpin’ polyP, actin’ brand new
Neuron ( IF 14.7 ) Pub Date : 2022-05-18 , DOI: 10.1016/j.neuron.2022.04.003 Kevin A Guttenplan 1 , Aaron D Gitler 2
中文翻译:
为什么你总是心情不好?Pumpin' polyP,actin' 全新
更新日期:2022-05-20
Neuron ( IF 14.7 ) Pub Date : 2022-05-18 , DOI: 10.1016/j.neuron.2022.04.003 Kevin A Guttenplan 1 , Aaron D Gitler 2
Affiliation
What causes neurons to die in neurodegenerative disease? In this issue of Neuron, Arredondo et al., 2022 report an unexpected culprit that may drive neuronal death in amyotrophic lateral sclerosis—an evolutionarily ancient energy-storage polymer called polyphosphate (polyP).
中文翻译:
为什么你总是心情不好?Pumpin' polyP,actin' 全新
是什么导致神经元在神经退行性疾病中死亡?在本期《神经元》中,Arredondo 等人,2022 年报告了一个意外的罪魁祸首,它可能导致肌萎缩侧索硬化症中的神经元死亡——一种进化上古老的能量储存聚合物,称为多磷酸盐 (polyP)。