Dendrite growth and side reactions on zinc anodes have been the main problems hindering the commercialization of aqueous zinc-ion batteries (ZIBs). The construction of an interface protective layer (IPL) has proved to be one of the effective ways to improve the stability of zinc anodes, but it remains a challenge to achieve multi-functionality. Herein, tetramethylammonium-intercalated Ti₃C₂T_x MXene (MX-TMA) coating with a low zinc nucleation barrier was in-situ constructed on the surface of zinc foil by a facile self-assembly method. It provides the IPL with abundant zincophilic sites and better hydrophilicity, which promotes the transport of Zn²⁺ for uniform electrodeposition and inhibits interface side reactions. Moreover, the directional deposition of zinc on the beneficial (002) plane guided by MX-TMA is further revealed. As a result, the lifespan of the zinc electrode under 2 mA cm^–2 is prolonged by 3600 h. Even under deep discharge (DOD_Zn≈85%), the MX-TMA@Zn anode can still achieve stable cycles for more than 450 h. Furthermore, the full battery assembled with the Mn-based cathode also demonstrated superior performance. This work provides an in-depth mechanism analysis and inspiration for IPL design, thus advancing the development and practical application of ZIBs.

锌负极上的枝晶生长和副反应一直是阻碍水系锌离子电池（ZIBs）商业化的主要问题。界面保护层（IPL）的构建已被证明是提高锌负极稳定性的有效方法之一，但实现多功能性仍然是一个挑战。在此，通过简便的自组装方法，在锌箔表面原位构建了具有低锌成核屏障的四甲基铵插层 Ti ₃ C ₂ T _{x MXene (MX-TMA) 涂层。}它为 IPL 提供了丰富的亲锌位点和更好的亲水性，从而促进了 Zn ^2+的传输用于均匀电沉积并抑制界面副反应。此外，进一步揭示了由MX-TMA引导的锌在有益（002）平面上的定向沉积。因此，2 mA cm ^–2下的锌电极寿命延长了 3600 小时。即使在深度放电（DOD _Zn ≈85%）下，MX-TMA@Zn 负极仍能实现 450 小时以上的稳定循环。此外，用锰基正极组装的完整电池也表现出优异的性能。该工作为 IPL 设计提供了深入的机理分析和启发，从而推动了 ZIBs 的开发和实际应用。