Lionaki et al. report that reducing mitochondrial protein import increases Caenorhabditis elegans lifespan, through a metabolic shift that enhances the conversion of glucose into serine. Here, I discuss the promise held by these findings in the framework of therapeutic approaches to metabolic and neurodegenerative diseases.

中文翻译：

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改变新陈代谢以延长寿命

莱昂纳基等人。报告说，通过增强葡萄糖转化为丝氨酸的代谢转变，减少线粒体蛋白质输入可以延长秀丽隐杆线虫的寿命。在这里，我讨论了这些发现在代谢和神经退行性疾病治疗方法框架中的前景。