Genu varum- a common symptom in achondroplasia- may lead to ankle valgus in children. Ankle valgus may be mitigated by tibiofibular synostosis, but this is not always the case. The mechanical environment around the growth plates plays an important role in ankle valgus. The purpose of this project is 1) to determine the strain through the distal fibular growth plate before and after tibiofibular synostosis, and 2) postulate whether the change in strain affects ankle valgus. This project measured the distal fibular strain in a porcine hind leg model. The lower legs of seven pigs were removed, instrumented with strain gauges, and loaded compressively in a material testing machine. Loads were applied at three phases: 1) the intact leg, 2) leg with fibula resected, and 3) leg with fibula resected and tibiofibular synostosis. Mean strains were compared between phases using a mixed affect model. The significance level was adjusted for multiple comparisons using the Bonferroni method. Phase 1, intact leg, had the highest strain value at 1247.9μɛ. In phase 2, the mean strain was 106.2μɛ. In phase 3, the compressive mean strain dropped to 477.4μɛ, which is 38% of the strain in phase 1. Standard error was 86.8μɛ; p < 0.001. Results indicate that more of the force through the leg is transmitted through the tibia after fibular resection and tibiofibular synostosis, which improves the balance of forces through the leg.

中文翻译：

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腓骨切除和关节融合后腿部力量分布得到改善

Genu varum - 软骨发育不全的常见症状 - 可能导致儿童踝关节外翻。踝关节外翻可能会因胫腓骨融合而得到缓解，但情况并非总是如此。生长板周围的机械环境在踝外翻中起着重要作用。该项目的目的是 1) 确定胫腓骨融合前后通过远端腓骨生长板的应变，以及 2) 假设应变变化是否影响踝外翻。该项目在猪后腿模型中测量了远端腓骨应变。七头猪的小腿被移除，安装应变仪，并在材料试验机中进行压缩加载。在三个阶段施加载荷：1) 完整的腿，2) 腓骨切除的腿，和 3) 腓骨切除和胫腓骨联合的腿。使用混合影响模型比较各阶段的平均应变。使用 Bonferroni 方法调整显着性水平以进行多重比较。第 1 阶段，完整的腿，应变值最高，为 1247.9μɛ。在第 2 阶段，平均应变为 106.2μɛ。在第 3 阶段，压缩平均应变降至 477.4μɛ，是第 1 阶段应变的 38%。标准误差为 86.8μɛ；p < 0.001。结果表明，在腓骨切除和胫腓骨联合后，更多的腿部力量通过胫骨传递，从而改善了腿部力量的平衡。压缩平均应变降至 477.4μɛ，是第一阶段应变的 38%。标准误差为 86.8μɛ；p < 0.001。结果表明，在腓骨切除和胫腓骨联合后，更多的腿部力量通过胫骨传递，从而改善了腿部力量的平衡。压缩平均应变降至 477.4μɛ，是第一阶段应变的 38%。标准误差为 86.8μɛ；p < 0.001。结果表明，在腓骨切除和胫腓骨联合后，更多的腿部力量通过胫骨传递，从而改善了腿部力量的平衡。