Background

Patient Specific Instruments (PSI) is currently a proven technique for bone tumor resection. In a previous publication, we analyzed the quality of margin resection of pelvic sarcoma resections with the use of PSI (by pathologic evaluation of the margins). In this new study, we compare preoperative resection planning and actual resection margins by MRI analysis of the resection specimens.

Methods

Between 2011 and 2020, 31 patients underwent bone tumor resection with the use of PSI. Preoperatively, the margins were planned with a software and PSI were made according to these margins. Postoperatively, the surgical resection specimens were analyzed with MRI. Resection margins were measured with the same software used in the preoperative planning.

Results

All margins were safe (free of tumor). The differences between preoperative planned margins and the obtained ones were within the range −5 to +5 mm. The correlation between planned margin and the obtained one was excellent (R² = 0.841; p < 0.0001).

Conclusions

This study demonstrates the accuracy of PSI. In our series, all resection margins were safe. A minimal 5 mm-margin has to be planned but a larger sample is needed to give recommendations.

中文翻译：

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使用患者专用器械进行骨肿瘤切除术的切缘质量

背景

患者专用仪器 (PSI) 目前是一种经过验证的骨肿瘤切除技术。在之前的一篇文章中，我们分析了使用 PSI（通过切缘的病理学评估）进行盆腔肉瘤切除术的切缘质量。在这项新研究中，我们通过对切除标本的 MRI 分析比较了术前切除计划和实际切除边缘。

方法

2011 年至 2020 年间，31 名患者使用 PSI 进行了骨肿瘤切除术。术前，使用软件规划切缘，并根据这些切缘进行 PSI。术后对手术切除标本进行MRI分析。使用与术前计划相同的软件测量切除边缘。

结果

所有切缘都是安全的（无肿瘤）。术前计划边缘与获得的边缘之间的差异在-5至+5 mm范围内。计划边际与获得的边际之间的相关性非常好（R ²  = 0.841；p < 0.0001）。

结论

这项研究证明了 PSI 的准确性。在我们的系列中，所有切缘都是安全的。必须计划至少 5 毫米的边距，但需要更大的样本来提供建议。