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Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2022-05-11 , DOI: 10.1016/j.chom.2022.04.003
Monowar Aziz 1 , Jose M Prince 2 , Ping Wang 1
Affiliation  

Necrotizing enterocolitis (NEC), a cause of death among premature babies, has defied therapeutics for decades. Bacterial analyses have expanded insights into NEC pathophysiology and roles of the gut microbiome. We discuss the contribution of the gut microbiome and potential therapeutics, notably lactadherin, that may promote gut homeostasis to alleviate NEC.



中文翻译:

肠道微生物群和坏死性小肠结肠炎:了解找到治疗方法的联系

坏死性小肠结肠炎 (NEC) 是早产儿死亡的一个原因,几十年来一直在挑战治疗方法。细菌分析扩大了对 NEC 病理生理学和肠道微生物组作用的认识。我们讨论了肠道微生物组和潜在疗法的贡献,尤其是乳粘素,它们可能促进肠道稳态以减轻 NEC。

更新日期:2022-05-12
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