Calcium Carbide as a Surrogate of Acetylene: Copper-Catalyzed Construction of 3-Methylene-2-arylisoindolin-1-ones,Asian Journal of Organic Chemistry

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Calcium Carbide as a Surrogate of Acetylene: Copper-Catalyzed Construction of 3-Methylene-2-arylisoindolin-1-ones
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2022-05-09 , DOI: 10.1002/ajoc.202200204
Haiyan Liu ₁ , Xinjie You ₂ , Fei Wen ₁ , Zeshuai Zhang ₁ , Zheng Li ₃

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Calcium carbide as a surrogate of acetylene was used to construct N-heterocycles in the presence of a copper catalyst. The cheap, safe, and easy-to-operate properties of calcium carbide compared with inflammable, explosive, and difficult-to-handle acetylene render the reactions easier to apply to various important synthesis.

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