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InFlamiN’ the brain in Alzheimer’s disease
Immunity ( IF 25.5 ) Pub Date : 2022-05-10 , DOI: 10.1016/j.immuni.2022.04.008
Jonas J Neher 1
Affiliation  

Although consistently implicated, the exact role of interferon (IFN) signaling in Alzheimer’s disease remains largely unexplored. Roy et al. now demonstrate that type I IFNs may drive cognitive dysfunction through acting not only on microglia but, surprisingly, also on neurons.



中文翻译:

InFlamiN' 阿尔茨海默病中的大脑

尽管一直受到牵连,干扰素 (IFN) 信号传导在阿尔茨海默病中的确切作用在很大程度上仍未得到探索。罗伊等人。现在证明 I 型 IFN 可能通过不仅作用于小胶质细胞而且令人惊讶地作用于神经元来驱动认知功能障碍。

更新日期:2022-05-11
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