Effective detection of Cys and Hcy plays an important role in the diagnosis of diseases. In this work, a novel indanone-based fluorescent probe INIAc-CN for sensitively and effectively detecting Cys and Hcy was developed. The probe exhibited weak fluorescence, but obvious fluorescent enhancement after reacted with Cys/Hcy. Moreover, the good anti-interference and low cytotoxicity of the probe made it successfully applied for monitoring Cys and Hcy of in living cells.

中文翻译：

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一种基于茚满酮的荧光探针，用于活细胞中 Cys/Hcy 的检测和成像

Cys和Hcy的有效检测对疾病的诊断具有重要作用。在这项工作中，开发了一种基于茚满酮的新型荧光探针INIAc-CN，用于灵敏有效地检测 Cys 和 Hcy。该探针与Cys/Hcy反应后荧光较弱，但荧光增强明显。此外，该探针良好的抗干扰性和低细胞毒性使其成功应用于监测活细胞中的Cys和Hcy。