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A Two-in-One Tumor in the Adrenal: A Functional Adrenocortical Adenoma with Myelolipomatous Differentiation
Fetal and Pediatric Pathology ( IF 0.7 ) Pub Date : 2022-05-10 , DOI: 10.1080/15513815.2022.2072423
Sunny Bhardwaj 1 , Rohit Sanjay Deshpande 2 , Santosh Kumar 2 , Suvradeep Mitra 1
Affiliation  

Abstract

Background

Adrenocortical adenoma (ADA) and myelolipoma are two common benign neoplasms of the adrenal cortex that have been reported to occur together.

Case report

A 14-year-old girl presented with the features of ACTH-independent endogenous Cushing syndrome. Abdominal CECT revealed a left adrenal 2.3 × 1.8 × 1.5 cm arterially enhancing nodular lesion with central hypodensity. Histologically, this was an ADA with oncocytic change and myelolipomatous differentiation/metaplasia.

Discussion/Conclusion

ADA with myelolipomatous differentiation/metaplasia can occur in the pediatric age group.



中文翻译:

肾上腺二合一肿瘤:功能性肾上腺皮质腺瘤伴骨髓脂肪瘤样分化

摘要

背景

肾上腺皮质腺瘤 (ADA) 和骨髓脂肪瘤是肾上腺皮质的两种常见良性肿瘤,据报道它们同时发生。

案例报告

一名 14 岁的女孩表现出非促肾上腺皮质激素依赖性内源性库欣综合征的特征。腹部 CECT 显示左侧肾上腺 2.3 × 1.8 × 1.5 cm 动脉强化结节性病变伴中央低密度。在组织学上,这是一种具有嗜酸细胞变化和骨髓脂肪瘤样分化/化生的 ADA。

讨论/结论

具有骨髓脂肪瘤样分化/化生的 ADA 可发生在儿科年龄组。

更新日期:2022-05-10
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