Chitosan is a biopolymer originating from renewable resources, with great properties which make it an attractive candidate for plenty of applications of contemporary interest. By manufacturing chitosan into nanofibers using the electrospinning method, its potential is amplified due to the enhancement of the active surface and the low preparation cost. Many attempts were made with the aim of preparing chitosan-based nanofibers with controlled morphology targeting their use for tissue engineering, wound healing, food packaging, drug delivery, air and water purification filters. This was a challenging task, which resulted in a high amount of data, sometimes with apparent contradictory results. In this light, the goal of the paper is to present the main routes reported in the literature for chitosan electrospinning, stressing the advantages and disadvantages of each of them. Special emphasis is placed on the influence of various electrospinning parameters on the morphological characteristics of the fibers and their suitability for distinct applications.

中文翻译：

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壳聚糖基纳米纤维的静电纺丝：从设计到应用前景

壳聚糖是一种源自可再生资源的生物聚合物，具有出色的特性，使其成为当代众多应用领域的有吸引力的候选者。通过使用静电纺丝法将壳聚糖制造成纳米纤维，由于活性表面的增强和较低的制备成本，其潜力被放大。为了制备具有受控形态的壳聚糖基纳米纤维，人们进行了许多尝试，以将其用于组织工程、伤口愈合、食品包装、药物输送、空气和水净化过滤器。这是一项具有挑战性的任务，会产生大量数据，有时会产生明显矛盾的结果。有鉴于此，本文的目的是介绍文献中报道的壳聚糖静电纺丝的主要路线，强调它们各自的优点和缺点。特别强调了各种静电纺丝参数对纤维形态特征的影响及其对不同应用的适用性。