This is the first of two installments examining early puberty in girls. The first paper will discuss secular trends in onset of puberty and the possible mechanisms to explain these developments. The potential etiologies examined will include the role of endocrine-disrupting chemicals and obesogens, the impact of body mass index and obesity, genetic and biologic pathways, and the influence of lifestyle behaviors. The second paper of the two-part series will examine the potential health impacts of early puberty on young and adult women and offer suggestions for clinical management and public health prevention.

中文翻译：

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女孩青春期提前的趋势及其可能的机制

这是研究女孩青春期早期的两期中的第一期。第一篇论文将讨论青春期开始的长期趋势以及解释这些发展的可能机制。检查的潜在病因将包括内分泌干扰化学物质和致肥胖物质的作用、体重指数和肥胖的影响、遗传和生物途径以及生活方式行为的影响。该系列文章由两部分组成，第二篇论文将探讨青春期早期对年轻和成年女性的潜在健康影响，并为临床管理和公共卫生预防提供建议。