Dopamine (DA) neurons in the ventral tegmental area bidirectionally regulate the activity of serotonin neurons in the dorsal raphe nucleus. Low-strength activity causes inhibition via dopamine receptor D2, whereas high- strength activity causes activation via dopamine receptor D1, and this circuit contributes to anorexia nervosa-like behaviors in mice.

中文翻译：

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用于治疗神经性厌食症的多巴胺-血清素回路

腹侧被盖区的多巴胺 (DA) 神经元双向调节中缝背核中血清素神经元的活性。低强度的活动通过多巴胺受体 D2 引起抑制，而高强度的活动通过多巴胺受体 D1 引起激活，并且该回路有助于小鼠的神经性厌食样行为。