Nocardia seriolae, a gram-positive branching filamentous bacterium, is the causative agent of fish nocardiosis. It mainly infects fish through gills, anus, lateral line or surface injury, resulting in a large number of white nodules in visceral organs and skin ulcerations. N. seriolae can infect about 42 species of fish and severely harm the aquaculture industry in many regions, particularly in Asia. Aiming to have a more comprehensive understanding about N. seriolae, the literature of N. seriolae before January 2022 was collected by searching nine databases and the current knowledge of the host diversity, drug resistance, genotype and phenotype, virulence factor, molecular detection and vaccine development of N. seriolae was summarized in this review. The future studies of N. seriolae are also prospected in order to help the research on the pathogenic mechanism and control of N. seriolae infection.

中文翻译：

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致病菌 Nocardia seriolae 的综述：病原学、发病机制、诊断和疫苗开发

Nocardia seriolae是一种革兰氏阳性分支丝状细菌，是鱼类诺卡氏菌病的病原体。主要通过鳃、肛门、侧线或体表损伤感染鱼类，引起内脏器官大量白色结节和皮肤破溃。N. seriolae可以感染大约 42 种鱼类，并严重危害许多地区的水产养殖业，尤其是在亚洲。为更全面地了解鲇鱼N. seriolae ，通过检索9个数据库及宿主多样性、耐药性、基因型和表型、毒力因子、分子检测和疫苗等方面的现有知识，收集了2022年1月以前关于鰤鱼的文献N. seriolae的发育总结在这篇评论中。并对今后对鰤鱼的研究进行了展望，以期对鳉鱼感染的致病机制和防治研究有所帮助。