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Death by differentiation: CD4+ T cells kick out suspicious stem cells
Cell Stem Cell ( IF 19.8 ) Pub Date : 2022-05-05 , DOI: 10.1016/j.stem.2022.04.013
Sara Tomei 1 , Cindy Audiger 1 , Shalin H Naik 1
Affiliation  

Antigen presentation is typically regarded as the domain of immune cells such as dendritic cells and B cells. Hernandez-Malmierca et al. (2022) upend this notion by observing that hematopoietic stem and progenitor cells process and present antigen via major histocompatibility class II as a means of CD4+ T cell-mediated immune surveillance.



中文翻译:

分化致死:CD4+ T 细胞剔除可疑干细胞

抗原呈递通常被认为是免疫细胞如树突状细胞和 B 细胞的域。埃尔南德斯-马尔米尔卡等人。(2022) 通过观察造血干细胞和祖细胞通过主要组织相容性 II 类处理和呈递抗原作为 CD4 + T 细胞介导的免疫监视手段来颠覆这一概念。

更新日期:2022-05-05
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