Compartmentalized micelles (CMs) are promising tailor-made soft matters that mimic natural designed structures and functions. Despite the structure of complex CMs, manipulating CM structures accessibly and reversibly remains elusive. Here, we report the fabrication of CMs via a generally valid noncovalent postmodification process. Starting from precursor micelles (PMs) based on one diblock copolymer, aromatic modification leads to the compartmentalization of PMs into well-defined spherical CMs. Control over compartment number, size and distribution in CMs, and segment distribution in their linear hierarchical assemblies is attained by simply tuning the postmodification degree and solvent composition. We also demonstrate the reversible transformation between PM and CMs during several heating–cooling cycles, which endows the micelles with potential in reversible functional transitions in situ close to nature’s capability. Moreover, both hierarchically assembled or ill-structured micelles can rearrange into homogeneous CMs after one heating–cooling cycle, featuring the postmodification guided compartmentalization strategy with unprecedented micelle reproducibility.

中文翻译：

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聚合物胶束的非共价后修饰引导可逆分隔

分隔胶束 (CM) 是有前途的定制软物质，可模仿自然设计的结构和功能。尽管有复杂的 CM 结构，但可访问和可逆地操作 CM 结构仍然是难以捉摸的。在这里，我们通过普遍有效的非共价后修饰过程报告了 CM 的制造。从基于一种二嵌段共聚物的前体胶束 (PM) 开始，芳族改性导致 PM 分隔成明确的球形 CM。通过简单地调整后修饰程度和溶剂组成，可以控制 CM 中的隔室数量、大小和分布，以及其线性分层组件中的片段分布。我们还展示了在几个加热 - 冷却循环期间 PM 和 CM 之间的可逆转变，就地接近大自然的能力。此外，分层组装或结构不良的胶束都可以在一个加热-冷却循环后重新排列成均匀的 CM，其特点是具有前所未有的胶束可重复性的改性后引导区室化策略。