Automated hematology analyzers generate accurate complete blood counts (CBC) results on nearly all specimens. However, every laboratory encounters, at times, some specimens that yield no or inaccurate result(s) for one or more CBC parameters even when the analyzer is functioning properly and the manufacturer's instructions are followed to the letter. Inaccurate results, which may adversely affect patient care, are clinically unreliable and require the attention of laboratory professionals. Laboratory professionals must recognize unreliable results, determine the possible cause(s), and be acquainted with the ways to obtain reliable results on such specimens. We present a concise overview of the known causes of unreliable automated CBC results, ways to recognize them, and means commonly utilized to obtain reliable results. Some examples of unreliable automated CBC results are also illustrated. Pertinent analyzer-specific information can be found in the manufacturers' operating manuals.

中文翻译：

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不可靠的自动全血细胞计数结果：原因、识别和解决方案。

自动化血液分析仪几乎可以对所有样本产生准确的全血细胞计数 (CBC) 结果。然而，每个实验室有时都会遇到一些样本，即使分析仪功能正常并且严格按照制造商的说明进行操作，也不会产生一个或多个 CBC 参数的结果或结果不准确。可能对患者护理产生不利影响的不准确结果在临床上是不可靠的，需要实验室专业人员的注意。实验室专业人员必须识别不可靠的结果，确定可能的原因，并熟悉在此类样本上获得可靠结果的方法。我们简要概述了不可靠的自动 CBC 结果的已知原因、识别它们的方法以及通常用于获得可靠结果的方法。还说明了一些不可靠的自动 CBC 结果示例。相关的分析仪特定信息可以在制造商的操作手册中找到。