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Symptom Association for Gastroesophageal Reflux Disease by pH Monitoring After Peroral Endoscopic Myotomy.
The American Journal of Gastroenterology ( IF 8.0 ) Pub Date : 2022-04-25 , DOI: 10.14309/ajg.0000000000001801
John M DeWitt 1 , William R Kessler 1 , John M Wo 1 , Sarah Stainko 1 , Anthony Perkins 2 , Destenee Dickason 1 , Mohammad A Al-Haddad 1 , Robert Siwiec 1
Affiliation  

INTRODUCTION There are limited data correlating symptoms with reflux episodes during pH studies after peroral endoscopic myotomy. METHODS Consecutive patients who underwent POEM followed up ≥6 months later by 48-hour ambulatory wireless pH testing off antisecretory therapy were identified. Reflux symptom association was defined as symptom association probability >95%. RESULTS The most frequent symptoms of heartburn (47.2%), cough (45.1%), and chest pain (39.6%) were associated with a positive reflux symptom association (symptom association probability >95%) in 20.9%, 17.1%, and 19.4%, respectively. DISCUSSION There is poor correlation between reported symptoms and esophageal acid exposure during pH testing after POEM.

中文翻译:

通过经口内窥镜肌切开术后 pH 监测胃食管反流病的症状关联。

简介 在经口内窥镜肌切开术后的 pH 研究期间,将症状与反流发作相关联的数据有限。方法 确定了连续接受 POEM 的患者,在 ≥ 6 个月后通过 48 小时动态无线 pH 测试进行抗分泌治疗。反流症状关联定义为症状关联概率 >95%。结果 最常见的胃灼热 (47.2%)、咳嗽 (45.1%) 和胸痛 (39.6%) 症状与反流症状阳性关联(症状关联概率 >95%)相关,分别为 20.9%、17.1% 和 19.4 %, 分别。讨论 POEM 后 pH 测试期间报告的症状与食管酸暴露之间的相关性较差。
更新日期:2022-04-25
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