Suberized and/or lignified (i.e. lignosuberized) periderm tissue appears often on surface of fleshy fruit skin by mechanical damage caused following environmental cues or developmental programs. The mechanisms underlying lignosuberization remain largely unknown to date. Here, we combined an assortment of microscopical techniques with an integrative multi-omics approach comprising proteomics, metabolomics and lipidomics to identify novel molecular components involved in fruit skin lignosuberization. We chose to investigate the corky Sikkim cucumber (Cucumis sativus var. sikkimensis) fruit. During development, the skin of this unique species undergoes massive cracking and is coated with a thick corky layer, making it an excellent model system for revealing fundamental cellular machineries involved in fruit skin lignosuberization. The large-scale data generated provides a significant source for the field of skin periderm tissue formation in fleshy fruit and suberin metabolism.

中文翻译：

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网状锡金黄瓜果皮周皮组织的代谢和蛋白质组学特征

由于环境因素或发育程序引起的机械损伤，皮下组织和/或木质化（即木质化）周皮组织经常出现在肉质果皮的表面上。迄今为止，木质素化的潜在机制在很大程度上仍然未知。在这里，我们将各种显微技术与包括蛋白质组学、代谢组学和脂质组学在内的综合多组学方法相结合，以确定参与果皮木质素化的新分子成分。我们选择研究软木塞金黄瓜 (Cucumis sativus var. sikkimensis) 果实。在开发过程中，这种独特物种的皮肤会发生大量开裂，并涂有厚厚的软木层，使其成为揭示果皮木质素化过程中涉及的基本细胞机制的优秀模型系统。