Aim

The aim of this study was to determine risk factors for the incidence of frailty in patients with distal radius fractures (DRFs).

Methods

In total, 116 patients (mean age, 66.3 ± 7.7 years) with DRFs were recruited. The participants were categorized into two groups, “frail” and “non-frail,” according to the presence or absence of frailty, respectively. The areal bone mineral densities (aBMDs) of the total hip, femoral neck, and lumbar spine were measured using dual-energy x-ray absorptiometry. The participants’ levels of resilience, depression, anxiety, nutritional intake, oral health-related quality of life, and social support were evaluated by self-reported questionnaires. The participants’ grip strength, gait speed, number of teeth present in their oral cavities, circumference of their upper arms and calves, and serum levels of vitamin D were also assessed.

Results

The participants in the “frail” group seemed to have lower aBMDs and muscle function and mass than those in the “non-frail” group. There were significant differences in grip strength, calf circumference, gait speed, and aBMD of the total hip, femoral neck, and lumbar spine between the groups. There were also significant differences in the levels of resilience and depression between the groups. A multivariate logistic regression analyses demonstrated that levels of sarcopenia, malnutritional status, and aBMDs of the total hip and femoral neck had significant relationships with the development of frailty in patients with DRFs.

Conclusions

An interdisciplinary approach involving the management of osteoporosis, sarcopenia, oral health, social relationships, and psychological support would be required for the proper management of DRF patients in preventing frailty.

中文翻译：

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桡骨远端骨折患者虚弱的危险因素

目标

本研究的目的是确定桡骨远端骨折（DRFs）患者衰弱发生率的危险因素。

方法

总共招募了 116 名患有 DRF 的患者（平均年龄，66.3 ± 7.7 岁）。根据是否存在虚弱，将参与者分别分为“虚弱”和“非虚弱”两组。使用双能 X 线骨密度仪测量全髋、股骨颈和腰椎的面积骨矿物质密度 (aBMD)。通过自我报告的问卷评估参与者的复原力、抑郁、焦虑、营养摄入、口腔健康相关生活质量和社会支持水平。还评估了参与者的握力、步态速度、口腔中的牙齿数量、上臂和小腿的周长以及血清维生素 D 水平。

结果

“虚弱”组的参与者似乎比“非虚弱”组的参与者具有较低的 aBMD、肌肉功能和质量。各组之间的握力、小腿围、步速和全髋、股骨颈和腰椎的aBMD有显着差异。各组之间的复原力和抑郁水平也存在显着差异。多变量逻辑回归分析表明，全髋和股骨颈的肌肉减少症、营养不良状态和 aBMD 水平与 DRF 患者的衰弱发展有显着关系。

结论

需要一种涉及骨质疏松症、肌肉减少症、口腔健康、社会关系和心理支持的跨学科方法，以正确管理 DRF 患者以预防虚弱。