An increasing recognition that brain and body are dynamically coupled has enriched our scientific understanding of mental health conditions. Peripheral signals interact centrally to influence how we think and feel, generating our sense of the internal condition of the body, a process known as interoception. Disruptions to this interoceptive system may contribute to clinical conditions, including anxiety, depression, and psychosis. After reviewing the nature of interoceptive disturbances in mental health conditions, this review focuses on interoceptive pathways of existing and putative mental health treatments. Emerging clinical interventions may target novel peripheral treatment mechanisms. Future treatment development requires forward- and back-translation to uncover and target specific interoceptive processes in mental health to elucidate their efficacy relative to interventions targeting other factors.

人们越来越认识到大脑和身体是动态耦合的，这丰富了我们对心理健康状况的科学理解。外围信号集中相互作用以影响我们的思考和感受方式，从而产生我们对身体内部状况的感觉，这一过程称为内感受。这种内感受系统的中断可能会导致临床状况，包括焦虑、抑郁和精神病。在回顾心理健康状况中内感受障碍的性质后，本综述重点关注现有和假定的心理健康治疗的内感受途径。新兴的临床干预措施可能针对新的外周治疗机制。