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Intraoperative hypothermia in the neonate population: risk factors, outcomes, and typical patterns
Journal of Clinical Monitoring and Computing ( IF 2.0 ) Pub Date : 2022-04-22 , DOI: 10.1007/s10877-022-00863-9
Man-Qing Zhang 1 , Peng-Dan Ying 1 , Yu-Jia Wang 2 , Jia-Lian Zhao 1 , Jin-Jin Huang 1 , Fang-Qi Gong 2
Affiliation  

The risk factors, outcomes, and typical patterns of intraoperative hypothermia were studied in neonates to better guide the application of insulation measures in the operating room. This retrospective study enrolled 401 neonates undergoing surgery under general anaesthesia with tracheal intubation, including abdominal surgery, thoracic surgery, brain surgery, and others. The study collected basic characteristics, such as age, sex, weight, birth weight, gestational week, primary diagnosis and American Society of Anaesthesiologists (ASA) grade. Perioperative data included preoperative body temperature, length of hospital stay, length of intensive care unit (ICU) stay, intubation time, postoperative bleeding, postoperative pneumonia, postoperative death, and total cost of hospitalization. Intraoperative data included surgical procedures, anaesthesia duration, operation duration, blood transfusion, fluid or albumin infusion, and application of vasoactive drugs. The incidence of intraoperative hypothermia (< 36 °C) was 81.05%. Compared to normothermic patients, gestational week (OR 0.717; 95% CI 0.577–0.890; P = 0.003), preoperative temperature (OR 0.228; 95% CI 0.091–0.571; P = 0.002), duration of anaesthesia (OR 1.052; 95% CI 1.027–1.077; P < 0.001), and type of surgery (OR 2.725; 95% CI 1.292–5.747; P = 0.008) were associated with the risk of intraoperative hypothermia. Patients with hypothermia had longer length of ICU stay (P = 0.001), longer length of hospital stay (P < 0.001), and higher hospital costs (P < 0.001). But there were no association between clinical outcomes and intraoperative hypothermia in the multivariable regression adjusted analysis. The lowest point of intraoperative body temperature was approximately 1 h 30 min. Then, the body temperature of patients successively entered a short plateau phase and a period of slow ascent. The greatest decrease in body temperatures occurred in preterm babies and neonates with preoperative hypothermia. The lowest core temperatures that occurred in neonates with preoperative hypothermia was lower than 35 °C. This study shows that there is a high incidence of intraoperative hypothermia in the neonate population. The intraoperative body temperature of neonates dropped to the lowest point in 1–1.5 h. The greatest decrease in core temperatures occurred in preterm babies and neonates with lower preoperative temperature.



中文翻译:

新生儿术中体温过低:危险因素、结果和典型模式

对新生儿术中低温的危险因素、结果和典型模式进行了研究,以更好地指导绝缘措施在手术室中的应用。本回顾性研究纳入了 401 名接受气管插管全麻手术的新生儿,包括腹部手术、胸外科手术、脑外科手术等。该研究收集了基本特征,例如年龄、性别、体重、出生体重、孕周、初步诊断和美国麻醉医师协会 (ASA) 分级。围手术期数据包括术前体温、住院时间、重症监护病房(ICU)住院时间、气管插管时间、术后出血、术后肺炎、术后死亡和住院总费用。术中数据包括手术过程、麻醉时间、手术时间、输血、输液或输白蛋白、血管活性药物的应用。术中低体温(< 36 °C)的发生率为 81.05%。与正常体温患者相比,妊娠周(OR 0.717;95% CI 0.577–0.890;P = 0.003)、术前体温(OR 0.228;95% CI 0.091–0.571;P = 0.002)、麻醉持续时间(OR 1.052;95% CI 1.027–1.077;P < 0.001)和手术类型(OR 2.725;95% CI 1.292–5.747;P = 0.008)与术中体温过低的风险相关。低体温患者的 ICU 停留时间更长 (P = 0.001),住院时间更长 (P < 0.001),住院费用更高 (P < 0.001)。但在多变量回归调整分析中,临床结果与术中低温之间没有关联。术中体温最低点约为 1 小时 30 分钟。随后,患者体温先后进入短暂的平台期和缓慢上升期。体温下降幅度最大的是术前体温过低的早产儿和新生儿。术前体温过低的新生儿的最低核心温度低于 35°C。这项研究表明,新生儿人群术中体温过低的发生率很高。新生儿术中体温在 1~1.5 h 降至最低点。核心温度下降幅度最大的是术前体温较低的早产儿和新生儿。患者体温先后进入短暂的平台期和缓慢上升期。体温下降幅度最大的是术前体温过低的早产儿和新生儿。术前体温过低的新生儿的最低核心温度低于 35°C。这项研究表明,新生儿人群术中体温过低的发生率很高。新生儿术中体温在 1~1.5 h 降至最低点。核心温度下降幅度最大的是术前体温较低的早产儿和新生儿。患者体温先后进入短暂的平台期和缓慢上升期。体温下降幅度最大的是术前体温过低的早产儿和新生儿。术前体温过低的新生儿的最低核心温度低于 35°C。这项研究表明,新生儿人群术中体温过低的发生率很高。新生儿术中体温在 1~1.5 h 降至最低点。核心温度下降幅度最大的是术前体温较低的早产儿和新生儿。术前体温过低的新生儿的最低核心温度低于 35°C。这项研究表明,新生儿人群术中体温过低的发生率很高。新生儿术中体温在 1~1.5 h 降至最低点。核心温度下降幅度最大的是术前体温较低的早产儿和新生儿。术前体温过低的新生儿的最低核心温度低于 35°C。这项研究表明,新生儿人群术中体温过低的发生率很高。新生儿术中体温在 1~1.5 h 降至最低点。核心温度下降幅度最大的是术前体温较低的早产儿和新生儿。

更新日期:2022-04-24
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