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Construction of boric acid-functionalized metal–organic frameworks for glycopeptide recognition in the serum of cervical cancer patients
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2022-04-20 , DOI: 10.1002/rcm.9314
Dongping Rao 1 , Baichun Wang 2 , Huizhen Zhong 1 , Yinghua Yan 2 , Chuan-Fan Ding 2
Affiliation  

Cervical cancer is one of the most common malignant tumors in women, and it is essential to explore potential biomarkers such as glycopeptides closely related to cancer in physiological samples of cervical cancer patients. Sample pretreatment is required before direct detection using mass spectrometry because there are certain limitations. Meanwhile, it is still highly desired to promote the functionalization and application of metal–organic framework (MOF)-derived materials.

中文翻译:

构建用于宫颈癌患者血清中糖肽识别的硼酸功能化金属有机框架

宫颈癌是女性最常见的恶性肿瘤之一,在宫颈癌患者生理样本中探索与癌症密切相关的糖肽等潜在生物标志物至关重要。由于存在一定的局限性,因此在使用质谱法直接检测之前需要进行样品预处理。同时,促进金属有机框架(MOF)衍生材料的功能化和应用仍然非常重要。
更新日期:2022-04-20
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