Epigenetic modifier gene mutations in chronic myeloid leukemia (CML) at diagnosis are associated with risk of relapse upon treatment discontinuation.,Blood Cancer Journal

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Epigenetic modifier gene mutations in chronic myeloid leukemia (CML) at diagnosis are associated with risk of relapse upon treatment discontinuation.
Blood Cancer Journal ( IF 12.9 ) Pub Date : 2022-04-20 , DOI: 10.1038/s41408-022-00667-9
Shady Adnan Awad _{1,

2,

3,

4} , Oscar Brück _{1,

2,

3} , Naranie Shanmuganathan _{5,

6,

7,

8,

9} , Timo Jarvinen _{1,

2} , Hanna Lähteenmäki _{1,

2} , Jay Klievink _{1,

2} , Hazem Ibrahim ₁₀ , Soili Kytölä ₁₁ , Perttu Koskenvesa ₁ , Timothy P Hughes _{5,

7,

9} , Susan Branford _{6,

7,

8,

9} , Matti Kankainen _{1,

2,

3} , Satu Mustjoki _{1,

2,

3}

Affiliation

Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.
Clinical Pathology Department, National Cancer Institute, Cairo University, Giza, Egypt.
Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia.
Department of Genetics and Molecular Pathology and Centre for Cancer Biology, SA Pathology, Adelaide, SA, Australia.
Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
School of Pharmacy and Medical Science, University of South Australia, Adelaide, SA, Australia.
School of Medicine, University of Adelaide, Adelaide, SA, Australia.
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
HUS Diagnostic Center, HUSLAB, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.