Although associations among borderline personality disorder (BPD), social rejection, and frontal EEG alpha asymmetry scores (FAA, a neural correlate of emotion regulation and approach-withdrawal motivations) have been explored in different studies, relatively little work has examined these relations during adolescence in the same study. We examined whether FAA moderated the relation between BPD features and rejection sensitivity following a validated social exclusion paradigm, Cyberball. A mixed, clinical-community sample of 64 adolescents (females = 62.5%; Mage = 14.45 years; SD = 1.6; range = 11-17 years) completed psychodiagnostic interviews and a self-report measure of BPD (Time 1). Approximately two weeks later (Time 2), participants completed a resting EEG recording followed by Cyberball. FAA moderated the relation between BPD features and overall feelings of rejection following Cyberball: individuals with greater relative left FAA had the highest and lowest feelings of social rejection depending on whether they had high and low BPD feature scores, respectively. Results remained after controlling for age, sex, gender, depression, and BPD diagnosis. These results suggest that FAA may moderate the relation between BPD features and social rejection, and that left frontal brain activity at rest may be differentially associated with those feelings in BPD. Findings are discussed in terms of the link between left frontal brain activity in the regulation and dysregulation of social approach behaviors, characteristic of BPD.

尽管不同的研究已经探讨了边缘性人格障碍 (BPD)、社交排斥和额叶脑电图 α 不对称评分（FAA，情绪调节和接近退缩动机的神经相关因素）之间的关联，但相对较少的工作在青春期期间检验了这些关系在同一项研究中。我们根据经过验证的社会排斥范式 Cyber​​ball，研究了 FAA 是否调节了 BPD 特征与拒绝敏感性之间的关系。64 名青少年的混合临床社区样本（女性 = 62.5%；M年龄 = 14.45 岁；SD= 1.6; 范围 = 11-17 岁）完成了心理诊断访谈和 BPD 自我报告测量（时间 1）。大约两周后（时间 2），参与者完成了静息脑电图记录，然后进行了 Cyber​​ball。FAA 调节了 Cyber​​ball 后 BPD 特征与整体拒绝感受之间的关系：FAA 相对左翼较大的个体的社交拒绝感受最高和最低，分别取决于他们的 BPD 特征得分是否高或低。在控制了年龄、性别、抑郁症和 BPD 诊断后，结果仍然存在。这些结果表明，FAA 可能会调节 BPD 特征与社交排斥之间的关系，并且休息时的左额脑活动可能与 BPD 的这些感受存在差异相关。