Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo.,Cell Research

当前位置： X-MOL 学术 › Cell Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo.
Cell Research ( IF 28.1 ) Pub Date : 2022-04-13 , DOI: 10.1038/s41422-022-00656-4
Mengjiao Li _{1,

2,

3,

4} , Zi-Wei Ye ₅ , Kaiming Tang _{5,

6} , Liang Guo _{1,

2,

3,

4} , Wenwen Bi _{2,

3,

4} , Yuyuan Zhang ₇ , Yan-Dong Tang ₇ , Guoguang Rong _{8,

9} , Mohamad Sawan _{8,

9} , Xin Yin ₇ , Ren Sun _{2,

3,

4,

10} , Shuofeng Yuan _{5,

6} , Bobo Dang _{2,

3,

4}

Affiliation

Fudan University, Shanghai, China.
Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
Center for Infectious Disease Research, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
CenBRAIN Lab., School of Engineering, Westlake University, Hangzhou, Zhejiang, China.
CenBRAIN Lab., Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.